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Studies regarding the removal of IgG reactive foods from the diet.

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The E.L.I.S.A. method of IgG Detection

 
The Brunel Laboratory detects food intolerances by measuring IgG antibody reactions using the ELISA method, a globally established technique for laboratory analysis that is over 40 years old and universally accepted as reliable and trustworthy. The Brunel service is based upon testing for IgG antibodies, and the assertion that a positive result indicates a trigger food that causes an inflammatory response leading to a symptom.
 

The Scientific Community

 
There are many studies within the scientific community that support our case for this - those that are summarised below are but a handful of published articles related to our field. As with any scientific hypothesis there will be studies that support and do not support a position, and we do invite our clients to not just consider the quantitative data that these studies and others provide but also to consider the qualitatatively measured human experiences and benefits of eliminating an IgG reactive food from the diet.

Our Research Projects

 
Our Laboratory is also involved in a number of research projects, both those initiated by ourselves, and those initiated by other institutions and organisations where we are a research partner. Some projects are entirely laboratory based, while others encompass both clinical and laboratory based aspects, as well as community and practitioner involvement.

Lee and Lee (2017) - Alterations of Food-specific Serum IgG4 Titers to Common Food Antigens in Patients with Irritable Bowel Syndrome.

Lee and Lee (2017) - Alterations of Food-specific Serum IgG4 Titers to Common Food Antigens in Patients with Irritable Bowel Syndrome.

Introduction

32 Patients diagnosed with IBS and 32 health controls were tested using and IgG antibody test.

Summary

Patient with IBS had significantly higher IgG antibody reactions than the control group.

Serum antibody levels to common foods are abnormally elevated in IBS patients.

Lee, H.S. and Lee, K.J., 2017. Alterations of Food-specific Serum IgG4 Titers to Common Food Antigens in Patients With Irritable Bowel Syndrome. Journal of neurogastroenterology and motility23(4), p.578.

Karakuła-Juchnowicz et al., (2017) - The role of IgG hypersensitivity in the pathogenesis and therapy of depressive disorders.
Virdee et al., (2015) - Food-specific IgG Antibody—guided Elimination Diets Followed by Resolution of Asthma Symptoms and Reduction in Pharmacological Interventions in Two Patients: A Case Report.
Lewis et al., (2012) - Eliminating Immunologically-Reactive Foods from the Diet and its Effect on Body Composition and Quality of Life in Overweight Persons.
Alpay et al (2010) - Diet restriction in migraine, based on IgG against foods: A clinical double-blind, randomised, cross-over trial.
Bentz et al. (2010) - Clinical relevance of IgG antibodies against food antigens in Crohn's disease: a double-blind cross-over diet intervention study
Rees et al. (2005) - A prospective audit of food intolerance among migraine patients in primary care clinical practice.
Atkinson, Sheldon, Shaath, et al (2003) - Food elimination based on IgG antibodies in irritable bowel syndrome: a randomised controlled trial.
Dixon HS. (2000) - Treatment of delayed food reactions based on specific immunoglobulin G testing